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What You Should Know About Fertility Preservation

Fertility preservation, in short, is an effort to preserve your ability to have a child by taking preconceived steps. The goal is to protect reproductive tissue and elements, so an individual can have a child later in life even if some event or care initiative would otherwise impede the process.

Reasons to Consider Fertility Preservation

Two types of fertility preservation exist: medically indicated and elective. Medically-indicated fertility preservation is done when an individual’s ability to conceive is or may be compromised because of certain diseases, health conditions, or treatments for certain illnesses. By contrast, elective fertility preservation is performed for more personal reasons, such as wanting to delay having a child until a certain age.

The most common reason people seek fertility preservation is age. For example, people who don’t want to have children until they are in their 40s may opt for preservation because age can affect fertility negatively. Other reasons for preservation can include:

  • Cancer treatment – Cancer may mean radiation, chemotherapy, or surgery that affects fertility
  • Reproductive health issues – Something like endometriosis may interfere with the ability to conceive
  • Autoimmune diseases – Rheumatoid arthritis, lupus, and other autoimmune diseases, as well as certain treatments, can interfere with fertility
  • Gender-affirming care – Sexual-affirming surgeries change reproductive capabilities

Types of Fertility Preservation Methods & Procedures

Fertility preservation is either removal of reproductive tissues or elements like eggs, sperm, or embryos, or working toward minimizing the impact of a type of medical treatment on the reproductive systems. Here is a closer look at the different types of fertility preservation.

Sperm Preservation

Sperm preservation is one of the most simple types of fertility preservation. The procedure involves collecting a semen sample and then freezing the contained sperm for future use. Sperm may be collected through masturbation, but may also be produced with vibratory stimulation or electroejaculation if an illness or condition affects a man’s ability to ejaculate naturally. The sperm may later be paired with an egg to form a viable embryo for in-vitro fertilization (IVF) or intrauterine insemination (IUI).

Egg Preservation

Egg preservation is also a common form of fertility preservation, and may be preferred over embryo preservation due to personal moral concerns. The eggs are harvested from the patient, safeguarded in cryogenic storage, and then thawed and used later for IVF. Unused eggs can be discarded or donated, depending on personal preferences.

Embryo Preservation

Embryo preservation is a common option for couples who want to have children but prefer to wait until later in life or face certain medical concerns. During embryo freezing, the embryos are created using IVF protocols and preserved cryogenically for later use.

Testicular and Ovarian Tissue Preservation

Ovarian and testicular tissue freezing is a more invasive form of fertility preservation but may be recommended in certain situations. During these surgical procedures, the tissues are actually surgically removed from the body and then placed in cryopreservation chambers. Later, the tissue is removed from cryopreservation. Ovarian tissue may be re-implanted, and then if those tissues return to normal function, conceiving may be possible. Unfortunately, testicular tissue freezing is a bit less common and still in its earliest stages. Tissues can be removed for preservation, but scientists are still learning about ways to harvest sperm cells from these tissues or use them for later reproduction.

Radiation Shielding

Radiation shielding may be done in different ways. However, the goal in terms of fertility preservation is always to use precise methodologies that shield the reproductive organs like the ovaries or testes during treatments involving radiation. Using lead shields was once the norm, but modern advancements in medical technology make it possible to take more effective steps. For example, radiographic equipment today emits only about a tenth of the amount of radiation as equipment from the 1970s. Additionally, further adjustments can potentially be made to the equipment to offer better levels of reproductive organ protection.

Ovarian Transposition

Ovarian transposition, medically referred to as oophoropexy, may be done to move the ovaries to a protected area before radiation treatment is performed. During this procedure, a surgeon will laparoscopically relocate the ovaries from your pelvic area and place them in another area of the abdomen. This temporary surgical solution takes the ovaries outside the field where radiation treatment may be targeted for something like uterine cancer. Once treatment is complete, the ovaries can be repositioned.

Risks of Fertility Preservation

Some fertility preservation procedures do come along with risks, even the mess-invasive procedures. For example, patients may face a risk of infection or bleeding during procedures used to collect sperm or eggs. Additionally, laparoscopic procedures may contribute to risks of infection or bleeding, and anesthesia used during these procedures may come along with risks. Any type of IVF, which may be used once preserved embryos are used, comes with the risk of problems like ectopic pregnancy or miscarriage, as well as conceiving multiples.

Ovarian stimulation, which may be used before egg collection, can lead to heightened estrogen levels, an increased risk of blood clots, and the potential of certain types of cancers. Ovarian hyperstimulation syndrome is also a possibility.

Ovarian transposition also comes along with perceived risks. Relocated ovaries can rotate, which can lead to problems, and ovarian cysts are possible.

The Success of Fertility Preservation

Fertility preservation has been successful in many regards for many patients. With all forms of preservation, the healthcare provider will build a treatment plan that provides the highest likelihood of successful pregnancy. Usually, IVF or IUI are the next steps after preservation, and those treatment options do have relatively good treatment outcomes.

The overall success of any IUI or IVF procedure varies on a number of factors. For example, with IVF, success can vary depending on:

  • Patient age at the time of treatment
  • Existing health conditions
  • Body mass index
  • Past successful pregnancies or miscarriages

Both ovarian tissue transplantation and ovarian transposition are relatively new and rare procedures. Therefore, there is not a great deal of information to offer in terms of successful pregnancies after the procedures. However, as of 2015, there were more than 35 live births reported after ovarian tissue preservation. Further, successful pregnancy has been reported by a few providers after ovarian transposition procedures.

Discuss Fertility Preservation with Experts at the Fertility Center

If you have concerns about fertility later in life due to health, age, gender reassignment, or otherwise, talking to a fertility specialist is the first step. Reach out to our team at the Fertility Center to schedule a consultation.